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MDMA (3,4-methylenedioxymethamphetamine), popularly known as ecstasy or, more recently, as Molly, is a synthetic, psychoactive drug that has similarities to both the stimulant amphetamine and the hallucinogen mescaline. It produces feelings of increased energy, euphoria, emotional warmth and empathy toward others, and distortions in sensory and time perception. MDMA was initially popular among White adolescents and young adults in the nightclub scene or at “raves” (long dance parties), but the drug now affects a broader range of users and ethnicities.
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Dosage and Administration
MDMA generally comes in the form of small tablets, capsules, or white powder. When found in tablet form (often referred to as “ecstasy”), it is common for MDMA to be combined with any of the following substances : MDMA, Caffeine, MDA, Methamphetamine, DXM, MDE, Pseudo/Ephedrine, Ketamine, BZP, and TFMPP. Chemical analysis of ecstasy tablets has found from 0 – 120 mg of MDMA as well as a variety of the above substances. Trying to calculate dosages from tablets containing unknown quantities of MDMA can be difficult, but a high quality tablet of street ecstasy (those containing MDMA alone) generally contains between 80 and 120 mg of MDMA. Some unusual tablets (especially in Europe) contain 150mg or more. The chart below shows what are considered recreational/therapeutic dosages for pure MDMA HCl (the most common crystalline form), measured in milligrams. Note that most Ecstasy and even crystalline MDMA is not 100% pure and may contain fillers or other drugs. See EcstasyData.org.
How Ecstasy Works
MDMA acts by increasing the activity of three neurotransmitters, serotonin, dopamine, and norepinephrine. The emotional and pro-social effects of MDMA are likely caused directly or indirectly by the release of large amounts of serotonin, which influences mood (as well as other functions such as appetite and sleep). Serotonin also triggers the re-lease of the hormones oxytocin and vasopressin, which play important roles in love, trust, sexual arousal, and other social experiences. This may account for the characteristic feelings of emotional closeness and empathy produced by the drug; studies in both rats and humans have shown that MDMA raises the levels of these hormones.
Like any drug, ecstasy can produce unexpected side effects.
The side effects include the following:
Sweating and chills.
Shaking and tremors.
Higher heart rate.
Increase in blood pressure.
Tension in mouth, face, and jaw.